Management of Pancuronium Bromide Administration

Description

• Clear, colourless solution 2 mg/ml (=2000 micrograms/ml) in 2 ml polyamps.
• Contains sodium chloride 6 mg/2 ml. No preservative added.

• Pancuronium bromide is charted under frequent drugs on the prescription chart in mcg/dose.

Administration

Slow IV Injection

1. Further dilution not required.
2. Filter prior to administration through a Pall 0.2 micron filter.
3. Administer by slow IV injection over 1 minute.
4. Compatible with NS and D5W. Also compatible with heparin.
5. Do NOT mix with other drugs, IV solutions, blood, or blood products.
6. Flush line with NS before and after injection of pancuronium.

Observation and Documentation

1. Administer only to intubated babies.
2. Observe for signs of adverse reactions.
3. Use comfort measures, sedatives, and analgesics as indicated (does NOT alter pain threshold).
4. Careful positioning and changes of position. Nurse baby on sheepskin.
5. Monitor oxygenation with blood gases and pulse oximetry.
6. Careful clinical observation. Pancuronium limits ability to assess the baby.
7. Provide eye protection PRN.
8. Monitor fluid balance.
9. Careful airway care to remove secretions.
10. Express bladder PRN.
11. Keep resuscitation equipment near bedside.

Storage

• Unopened store in refrigerator 2-8°C. May be out of refrigerator for transport. Discard at end of transport if not used.
• Discard ampoule after use.

Selected References