Exchange Transfusion
Preparation and Care of Blood/Line

 

Reviewed by K. Brokenshire & Pita Birch
December 2009
Clinical Guidelines Back Newborn Services Home Page

Nursing staff responsibility:  Follow the steps below for correct preparation and care of Blood/Line

Steps Actions
1
2
  • Donor blood should be:
    • CMV negative.
    • Haemolysin negative.
    • Partially packed (i.e.100ml plasma removed).
    • Less than 5 days old.
    • Irradiated to reduce risk of Graft versus Host disease.  Blood has a 24 hour expiry time post irradiation, as K+ level rises.
3
  • Donor blood packs should be mixed every 15 minutes by gently squeezing the bag during transfusion to prevent settling of red blood cells and to prevent infant receiving mostly plasma at end of each unit.
  • Mix the blood before taking the samples.
  • If the exchange is interrupted, remove the blood from the blood warmer and from under the radiant heater to prevent overheating.