Exchange Transfusion
Specimens - Donor, Pre-exchange, During Exchange, and Post-Exchange

 

Reviewed by K. Brokenshire & Pita Birch
December 2009
Clinical Guidelines Back Newborn Services Home Page

Nursing staff responsibility:  The following specimens must be collected.

Steps

Action

1

  • Donor Blood Specimens:
    • Mix blood well.
    • Specimen is to be taken from each unit as soon as it arrives.
    • Collect 0.3ml into a blood gas syringe and record haemoglobin and K+.
    • Blood should not be used if potassium result is:
        >15mmol/L in well babies
        >10mmol/L in small sick babies

2

  • Pre-Exchange Patient Specimens:
    • Collect 0.3ml for arterial blood gas, Na, K, Ca and glucose levels.
    • Collect 0.3ml and send for FBC and differential.
    • Collect 0.7ml and send for urea, creatinine, bilirubin (total and direct).
    • Before second and repeat exchanges or where there are clotting abnormalities, collect 0.8ml into buffered citrate micro-container (obtained from lab), send for coagulation screen.
3
  • During Exchange Specimen:
    • Blood gas, electrolytes and glucose are tested as ordered.
4
  • Post-Exchange Patient Specimens: (take from the last few ml of the exchange out volume)
    • Collect 0.3ml in blood gas syringe, test for gas, Na, K, Ca, Glucose.
    • Collect 0.3ml and send for FBC and differentials
    • Collect 0.7ml and send for urea, bilirubin (total and direct).

    • Coagulation screen should be performed if more than one exchange.
5
  • All patient specimens are taken via the 3 way tap closest to the arterial line out catheter.