Platelet Concentrates

• Single random platelet concentrates are made from individual units of CMV negative whole blood.
• These platelet concentrates are resuspended in 50 - 60mls of plasma with each concentrate containing at least 5.5 x 10¹⁰ platelets, 1-2 x 10⁸ lymphocytes and some granulocytes and a small number of red cells.

Indications

Vary for individuals but below are guidelines:

• Thrombocytopenia (platelets reduced)
• Thrombasthaenia (platelets not functioning)

Click here to link to the Thrombocytopenia guideline for guidelines on what levels to transfuse at.

Parental Consent

• Informed consent required.
• Parent signs on Agreement to Treatment Forms (CR0111).

Prescribing of Platelets

• Prescribed on the blood transfusion/IV fluid chart (CR5541).

Ordering

• One unit of platelet concentrate can be ordered over 24 hours for one baby without contacting the NZBS Medical Officer.  However, for longer, or daily concentrates, please discuss with the NZBS Medical Officer.
• Remembering that every effort must be made to reduce exposure of neonatal patients to blood products and separate blood donations.

Dose

• Usually 10-15ml/kg.
• Usually given 30-60 minutes.

Shelf Life

• Shelf Life of 5 days only.

Checking, Administration, Monitoring and Documentation

• As for blood and blood products.
• Checking
• Administration
• Monitoring
• Documentation

Adverse Reactions

• See Transfusion Reactions.

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