Blood and Blood Products
Transfusion Reactions

 

Authorised by Charge Nurse - Newborn
April
2006
Clinical Guidelines Back Newborn Services Home Page
Transfusion Reactions Management

Transfusion Reactions

Type of Reaction Symptoms and Signs
Febrile
  • Pyrexia, rigors.
Circulatory Overload
  •  Increase in blood pressure, heart rate and respirations.
  • Pulmonary oedema, dyspnoea, increase in urinary output
Allergic
  • Urticaria, facial oedema, dyspnoea, hypotension
Haemolytic
  • Collapse with hypotension.
  • Shock, pyrexia, rigors, haemoglobinuria, haemoglobinaemia, oliguria, later uraemia.
Infected Blood
  • Pyrexia, profound collapse and shock, pallor, dyspnoea, low blood pressure, rapid pulse.

Management of Transfusion Reactions

Step Action
1 STOP THE TRANSFUSION IMMEDIATELY.
2 The Nurse contacts the Doctor/NS-ANP immediately the baby manifests any sign of reaction.
3 Babies vital signs must be recorded and documented.
4 Maintain patency of cannula using a new giving set and 0.9% sodium chloride.
5 Check label and recipient ID information is correct.
6 Send NZBS Notification and Investigation of Adverse Transfusion form and the blood product with IV giving set attached in a plastic bag to the Blood Bank immediately to allow investigation of the cause of the reaction.
7 Notify Blood Bank by phone; discuss urgency of follow-up tests and further transfusion needs.
8 Take a sample of baby’s blood (from a different vein).  Blood group serology and EDTA – in purple top tube - send to Blood Bank.  FBC + serum biochemistry.
9 Consider need for blood cultures is sepsis suspected.  Blood gases if respiratory distress present.  Urine check for haemoglobinuria.  Coagulation screen if bleeding.
10 Parents of baby are informed.


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