C-Reactive Protein (CRP)
Indications and Interpretation 


Reviewed by Clinical practice Committee
Clinical Guidelines Back Newborn Services Home Page





1 Ehl, S., et al.  C-reactive protein is a useful marker for guiding duration of antibiotic therapy in suspected neonatal bacterial infection. Pediatrics, 1997; 99:216-21.
2 Franz, A.R., et al.  Reduction of unnecessary antibiotic therapy in newborn infants using interleukin-8 and C-reactive protein as markers of bacterial infections. Pediatrics 1999. 104:447-53.
3 Benitz, W.E., et al., Serial serum C-reactive protein levels in the diagnosis of neonatal infection. Pediatrics 1998;102:E41.
4 Lacaze-Masmonteil T, Rosychuk RJ, Robinson JL. Value of a single C-reactive protein measurement at 18 h of age. Arch Dis Child Fetal Neonatal Ed. 2014 Jan;99(1):F76-9
5 Hofer, N, et al. An Update on the Use of C-Reactive Protein in Early-Onset Neonatal Sepsis:Current Insights and New Tasks. Neonatology 2012;102:2536