Contraindications

Serious reaction following a previous dose of Pertussis vaccine, namely:

• Encephalopathy within seven days
• Immediate severe anaphylactic reaction to the vaccine.
• Presence of an evolving neurological disorder until stabilised.

Other

• Reaction following previous dose (not shown to be associated with long term sequelae)
• Temperature of >40.5°C within 48 hours not due to another identifiable cause.
• Persistent inconsolable crying lasting >3 hours.
• Convulsions with or without fever occurring within 3 days of vaccination. A family history of convulsive fits do not constitute contraindications.
• Collapse or shock-like state (hypotonic, hyporesponsive episode – HHE) within 48 hours.
• Administer with caution to babies with thrombocytopenia.
• Consider delaying vaccine if baby on steroids as may have reduced immunogenicity (discuss with consultant).

Possible adverse effects of Immunisations

The Nurse will ensure the following effects are observed and reported to Charge Nurse, Registrar/NS-ANP and appropriate management instituted.

 

Step	Action
1	Localised reaction. Redness or swelling.
2	Feed intolerance, (e.g. vomiting).
3	‘Grizzliness’.
4	Febrile (core temp of 37.5°C or greater). Stat dose of Paracetamol liquid may be prescribed.

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