|Reviewed by Clinical
Merck, Sharpe and Dohme (New Zealand) Ltd
Live attenuated oral vaccine
Rota Teq® induces antibodies against five serotypes of rotavirus, G1-4 and P.
Exact mechanism unknown2.
- Prevention against rotavirus infection
- There should be a minimum of 4 weeks between doses
- Routine Immunisations are given independently of the Rota Teq timing.
- Known history of allergy to Rota Teq® or any of its constituents
- Infants with severe immune-deficiency syndrome.
- Infants who have suffered from intussusception.
- Rotavirus vaccines should not be given to infants with uncorrected
congenital malformation of the GI tract
- Use with caution in patients with a history of gastroenteritis
- Use in infants with stomas to be discussed on individual basis with ID
team and neonatal specialist
- A pale yellow, clear liquid, contained in a squeezable, 2ml, plastic,
(latex free), dosing tube.
- A 2 mL single oral dose is given at 6 weeks, 3 months and 5 months
- The first dose must be given before 15 weeks of age (i.e. 14 weeks and 6
days) and the course of 3 vaccinations must be completed before the child is
8 months old.1,2,3,4
- If a baby is discharged between 6 weeks to 15 weeks of age then
vaccination should be considered on the day of discharge to allow timely
vaccination but avoid the risk of shedding the virus in the stool in the
- If a baby is unlikely to be discharged before 15 weeks of age the
vaccination should be considered/discussed at the time of the second routine
vaccination to ensure that Rotavirus vaccination is not missed.
- There should be a minimum of 4 weeks between doses.
- If a dose is regurgitated or vomited do not repeat the dose.3,4
- Rota Teq® may be given at the same time as other routine
childhood vaccinations. Prevenar 13®, Infanrix-hexa®
- Rota Teq® may also be given at the same time as other
live attenuated vaccines e.g. BCG
- No need to withhold Rota Teq® after receiving blood
products as is required for other parenteral live attenuated vaccines
- Infants who are receiving post natal steroids or pre/post
cardiac surgery shall be discussed on individual basis with ID team and
neonatal specialist but as a general rule Rota Teq® administration would be
delayed until high dose steroids are completed.
- Ensure use of universal infection control precautions when handling
infants who have recently received rotavirus vaccination to avoid any risk
of contamination or faecal-oral spread.
- Discard any remaining solution 14 days after reconstitution
- Rota Teq® should be protected from light and stored in the vaccine
fridge at 2-8oC. Do not freeze
- In Australia immunisation reduced the rate of hospitalisation for
rotavirus infection by 70%
- It is expected the vaccination will give protection against rotavirus
for 3 years following the last dose.3,4
- Infants who have already had rotavirus should still receive Rota Teq®
- The reason for the recommended dosing schedule is because this is the
patient group that the vaccine has been tested in.2,3,4
- Each vaccine dose contains sucrose, sodium citrate, sodium phosphate
monobasic monohydrate, sodium hydroxide, polysorbate 80 and also culture
media. There are no preservatives or thiomersal present.2
Rotavirus and Rota Teq® vaccine; Factsheet for vaccinators and health