Premedication for Intubation
Quick Reference Guide

 

Reviewed by Carl Kuschel
November 2007
Clinical Guidelines Back Newborn Services Home Page

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Drugs for Intubation - Quick Reference Guide

Medication
Concentration

Atropine
(600mcg/ml)

Fentanyl
(100mcg/2ml)

Suxamethonium
(100mg/2ml)

Weight (g) 20mcg/kg IV 4mcg/kg IV 2mg/kg IV

500

0.02ml

0.04ml

0.02ml

750

0.03ml

0.06ml

0.03ml

1000

0.03ml

0.08ml

0.04ml

1250

0.04ml

0.10ml

0.05ml

1500

0.05ml

0.12ml

0.06ml

1750

0.06ml

0.14ml

0.07ml

2000

0.07ml

0.16ml

0.08ml

2500

0.08ml

0.20ml

0.10ml

3000

0.10ml

0.24ml

0.12ml

3500

0.12ml

0.28ml

0.14ml

4000

0.13ml

0.32ml

0.16ml

4500

0.15ml

0.36ml

0.18ml

5000

0.17ml

0.40ml

0.20ml


Notes:
  1. Appropriate dose must be charted on Drug Prescription Chart.  Please chart the concentration of the medication, as well as the volume.
  2. Choose the weight most appropriate for the baby (above).
  3. Suxamethonium should not be given in the presence of significant hyperkalaemia.
  4. Drugs should be given in the order of:
    1. Atropine (wait for a rise in HR of >20bpm)
    2. Fentanyl (wait at least 30 seconds for onset of action)
    3. Suxamethonium
  5. In the event of an unsuccessful intubation attempt, Suxamethonium can be administered again.
    Atropine and Fentanyl doses should not be repeated.
  6. Fentanyl should be given as a slow push (rapid pushes may cause chest wall rigidity). The onset of action is rapid.
  7. Dosage range for Suxamethonium 1 to 3 mg/kg IV