Narcotic Depression in the Newborn Infant


Re-issued by Clinical Practice Committee
Mar 2015
Clinical Guidelines Back Newborn Services Home Page
Treatment of Narcotic Depression Observation and Documentation References

Treatment of Narcotic Depression

  1. When indicated, resuscitation must be instituted without delay, usually before naloxone administration.
  2. Treat narcotic depression with naloxone (Narcan) intramuscularly.
  1. Dose 0.1-0.2mg/kg per dose, IM.
  2. Naloxone comes in ampoules containing 0.4mg/ml.
  3. Intramuscular administration is preferable. The onset of action is almost as rapid as with IV administration, but the duration of action is much longer.

See Naloxone Drug Protocol for more details.

Observation and Documentation



Committee on Drugs. American Academy of Pediatrics. Pediatrics 1989;83:803.


Wiener PC et al. Br Med J 1977;2:228-31.


Brice JEH et al. Arch Dis Child. 1979;54:356-61

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