ADRENALINE HYDROCHLORIDE
Adrenaline
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Reviewed by NICU and Pharmacy |
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November 2011 |
Management of Adrenaline Administration
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Prescription
- Slow intravenous push, intratracheal and
intracardiac adrenaline are charted on the stat page of the drug
prescription chart in ml/dose.
Continuous Infusions:
Charted on fluid chart giving:
- rate in ml/hour
- dose in nanograms/kg/minute
Also charted on drug chart under continuous
infusions giving:
- amount of drug to be added
- base fluid, type and volume
Administration
Administration of Intratracheal Adrenaline for
Resuscitation
- Administered by doctor / NS-ANP
or a nurse with neonatal IV Drug Certification.
- Dilute in 1-2ml of NS.
- Instil into endotracheal tube. May be
repeated as necessary.
Continuous Infusion (Use 1:10,000 strength
Adrenaline)
- Administered by a nurse with
Neonatal IV Drug Certification.
- Dilute prior to administration.
- Do NOT use discoloured solutions.
- Filter prior to administration through a
Pall 0.2 micron filter.
- Compatible with D5W, D10W and NS.
Incompatible with alkaline solutions/drugs.
- Do NOT mix with other drugs, blood
or blood products.
- Protect from light during administration. Wrap tubing in tinfoil and cover syringe.
- Administer via a syringe pump.
- Give through a central venous line (UVC, Longline, or Surgical CVL).
Slow Intravenous Push
- Is administered by the doctor / NS-ANP. In an
emergency situation the nurse may administer under the direct supervision of
the doctor / NS-ANP present.
- Further dilution is not necessary. Do not use discoloured solutions.
- Administer IV by slow push over 5 minutes.
- Filter prior to administration through a Pall 0.2 micron filter.
- Compatible with NS, D5W and D10W.
Incompatible with alkaline solutions/drugs.
- Do NOT mix with other drugs, IV solutions, blood or blood products.
- Flush with NS before and after administration of adrenaline.
Administration of Intracardiac Adrenaline
- This is a medical staff only procedure.
- To be administered with a 22 gauge needle.
Nursing Considerations
- Observe IV site for signs of infiltration.
- Continuous blood pressure monitoring or 5 minute BP recordings.
- Continuous cardiorespiratory monitoring.
- Document vital signs hourly and PRN.
- Assess need for endotracheal suctioning.
Mucous plugs may become more difficult to dislodge.
Storage
- At room temperature.
- Protect from light.
- Discard ampoule after opening.
- Continuous infusions.
No stability data available for dilute solutions of adrenaline. Change
solutions 8 hourly or more frequently if BP not maintained.
References
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1
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Guys, Lewisham and St Thomas Hospitals, Paediatric Formulary, 3rd
Edition 1993, p11. |
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2
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Royal Children's Hospital, Melbourne. Paediatric Pharmacopaeia 11th
Edition 1994, p5. |