HYDROCORTISONE SODIUM SUCCINATE

Solu-Cortef

Reviewed by Dr Jane Harding, Brenda Hughes, and Dorothy Cooper
August 1996
Dose and Pharmacology Newborn Drug Protocol Index Newborn Services Home Page

 

Management of  Hydocortisone Administration

Description

Oral

Prescription

Administration

Slow IV Infusion

  1. Press down on plastic activator to force diluent into the lower compartment. Gently agitate to mix solution.
  2. Dilute immediately prior to use to 1 mg/ml in NS or D5W.
  3. Administer by slow IV infusion over 30 minutes. Filter prior to administration through a Pall 0.2 micron filter.
  4. Is compatible with D5W and NS.
  5. Do NOT administer with other drugs, IV solutions, blood or blood products.

IM Injection

  1. Further dilution not necessary.

Oral

  1. Follow instructions on bottle label.
  2. Administer at feed times.

Observation and Documentation

  1. Monitor for signs of adverse effects.
  2. 8 hourly urinalysis for glycosuria.
  3. Weigh daily.
  4. Monitor vital signs including blood pressure.
  5. Monitor fluid balance.
  6. Assess baby closely for signs of infection.

Storage

Selected References

1 Pawlak RP, Herfert LAT. Drug administration in the NICU. 2nd ed 1991 Neonatal Network p124-125.
2 Prescribing information (product disclosure). The Upjohn Company. December 1994.