Reviewed by Dr
Carl Kuschel and Helen Lamb (NSANP)
Management of Potassium Administration
- IV preparation. Clear colourless solution 1mmol/ml (0.75 gm in 10ml).
- Oral preparation - clear and colourless 2 mmol/ml (osmolality
- For an infusion to correct symptomatic hypokalaemia, charted on stat page of prescription chart stating mmol/dose and fluid to be diluted in type and
volume, time to be infused.
- For oral supplementation, charted on prescription chart stating ml/dose,
frequency, and mmol/kg/day.
Volumetric infusion pump.
- Charted on fluid chart only stating 1 molar potassium chloride and volume to be added.
- Charted on prescription chart stating ml/dose.
- For central line administration, dilute prior to use to 1 mmol in 12.5ml
(80mmol/L) with NS, D5W or D10W. Stronger solutions are unacceptable. Mix
- For peripheral line administration, dilute prior to use to 1mmol in 25ml
(40mmol/L) with NS, D5W or D10W. Mix well.
- Administer by slow IV infusion
Y injection port of minibore tubing. Keep IV
fluids running to ensure further dilution of potassium. Compatible for
co-infusion with IVN at Y injection site.
- Do NOT mix with other drugs, blood or blood products.
- Shake well before use.
- Administer with feeds to decrease likelihood of gastro-intestinal reactions.
Observation and Documentation
- Monitor for adverse reactions.
- Observe site closely for extravasation.
- Continuous cardiac monitoring during administration of slow IV infusion by syringe pump.
- Monitor K+ levels closely following slow infusions.
- Assess for gastrointestinal intolerance of oral potassium.
- At room temperature <30°C. Discard ampoule after use.
- Oral: Store in refrigerator. Discard after 1 week.
Trissel LA. Handbook on Injectable Drugs
(14th Ed), 2007. p1370-1
Phelps SJ, Hak EB. Pediatric Injectable
Drugs (7th Ed), 2004. p332-3.
Tubman M, Majumadar SR, Lee D, Friesen C,
Klassen TP. Best practices for safe handling of products containing
concentrated potassium. BMJ 2005;331:274-7.
Neonatal Formulary 5: Drug use in pregnancy
and the first year of life. BMJ Books (Blackwell Publishing, Oxford)