MICONAZOLE

Daktarin

Reviewed by Carl Kuschel
May 2006
Dose and Pharmacology Newborn Drug Protocol Index Newborn Services Home Page

Management of Miconazole Administration

Description

Prescription

Administration

Oral

  1. Gel can be drawn up in a syringe.
  2. Apply gel to all areas in the mouth with a syringe.
  3. Administer after a feed.

Topical

  1. Apply cream to mycotic lesions with a swab or applicator.

Nursing Considerations

  1. Observe for signs of adverse effects.
  2. Provide frequent oral care.
  3. Observe for signs of airway obstruction.
  4. If dummy is used, change daily to avoid reinfection.
  5. Treatment should be reviewed at 5 days. If there has been a clinical success, treatment should be discontinued. Otherwise, treatment should be continued for up to a total of 12 days. If treatment has been unsuccessful at this point, an alternative treatment should be considered.

Storage

References

1

Hoppe JE, and the antifungals study group. Treatment of oropharyngeal candidiasis in immunocompetent infants: a randomized multicenter study of miconazole gel vs. nystatin suspension. Pediatr Infect Dis J 1997;16:288-93

2

Hoppe JE, Hahn H, and the antimycotics study group. Randomized comparison of two nystatin oral gels with miconazole oral gel for treatment of oral thrush in infants. Infection 1996;24(2):136-139

3

Saunders R (ed). New Ethicals Compendium. Auckland, Adis Press 1992. 4th edition. Pages 898-900

4

Koldin MH, Medoff G. Antifungal chemotherapy. Pediatr Clin North Am 1983; 30:49-61.

5

Jansen-Cilag Pty Ltd.  Datasheet and communication.  27 April, 2006.