PORACTANT ALPHA

Curosurf

Reviewed by Mariam Buksh
July 2010
Dose and Pharmacology Newborn Drug Protocol Index Newborn Services Home Page

Management of Poractant Administration

Description

Prescription

Administration

  1. Warm in hand for 8 minutes or at room temperature for 20 minutes.
  2. Vial should be gently turned upside down before use.  Do NOT SHAKE.
  3. Draw up dose into 3-5ml syringe through a large needle. DO NOT filter.
  4. Doctor/NS-ANP administers surfactant directly into ETT.
  5. Avoid suctioning for 6 hours if possible. Subsequent suctioning should be as per baby's normal routine and/or on consultation with medical staff.

Nursing Considerations

  1. Monitor heart rate, SaO2, colour, chest movement and document.
  2. After administration, monitor closely to prevent post-dose hyperoxia and hypocarbia.
  3. Monitor arterial blood gas (ABG) as ordered by doctor/NS-ANP.

Storage

References

1 Sweet DG et al. European consensus guidelines on the management of neonatal respiratory distress syndrome in preterm infants - 2010 update. Neonatology 2010;97:402-417.
2 Poractant alpha (Curosurf) product information sheet. Douglas pharmaceuticals.
3 Poractant alpha (Curosurf): Product monograph.  Chiesi Farmaceutiici, Parma, Italy.
4 Halliday HL. History of surfactant from 1980. Biol Neonate 2005;87:317-322