Reviewed by Mariam Buksh
July 2010
Dose and Pharmacology Newborn Drug Protocol Index Newborn Services Home Page

Management of Poractant Administration




  1. Warm in hand for 8 minutes or at room temperature for 20 minutes.
  2. Vial should be gently turned upside down before use.  Do NOT SHAKE.
  3. Draw up dose into 3-5ml syringe through a large needle. DO NOT filter.
  4. Doctor/NS-ANP administers surfactant directly into ETT.
  5. Avoid suctioning for 6 hours if possible. Subsequent suctioning should be as per baby's normal routine and/or on consultation with medical staff.

Nursing Considerations

  1. Monitor heart rate, SaO2, colour, chest movement and document.
  2. After administration, monitor closely to prevent post-dose hyperoxia and hypocarbia.
  3. Monitor arterial blood gas (ABG) as ordered by doctor/NS-ANP.



1 Sweet DG et al. European consensus guidelines on the management of neonatal respiratory distress syndrome in preterm infants - 2010 update. Neonatology 2010;97:402-417.
2 Poractant alpha (Curosurf) product information sheet. Douglas pharmaceuticals.
3 Poractant alpha (Curosurf): Product monograph.  Chiesi Farmaceutiici, Parma, Italy.
4 Halliday HL. History of surfactant from 1980. Biol Neonate 2005;87:317-322