Ventolin, Respax

Reviewed & Approved by Clinical practice Committee
August 2015
Dose and Pharmacology Newborn Drug Protocol Index Newborn Services Home Page

Administration of Nebulised Salbutamol


Clear, colourless respirator solution 1 mg/ml in 2.5 ml sterinebs. Always make up to a total of 2 ml with normal saline.
Be aware: salbutamol comes in two different preparations:

They are not interchangeable



Nebulised via face mask

Nebulised via endotracheal tube – Babylog 8000/VN500

Observation and Documentation


1 Yaseen H, Khalaf M, Dana A, Yaseen N, Darwich M. Salbutamol versus cation-exchange resin (kayexalate) for the treatment of nonoliguric hyperkalemia in preterm infants. Am J Perinatol. 2008;25:193–7.
2 Singh BS, Sadiq HF, Noguchi A, Keenan WJ. Efficacy of albuterol inhalation in treatment of hyperkalemia in premature neonates. J Pediatr. 2002;141:16–20. 
3 Johnson M. Beta2-adrenoceptors: mechanisms of action of beta2-agonists. Paediatr Respir Rev. 2001;2:57–62.
4 Doyle LW, Roberts G, Anderson PJ. Changing long-term outcomes for infants 500-999 g birth weight in Victoria, 1979-2005. Arch Dis Child Fetal Neonatal Ed. 2011; 96:403-7.
5 Garner SS, Southgate WM, Wiest DB, Brandeburg S, Annibale DJ. Albuterol delivery with conventional and synchronous ventilation in a neonatal lung model. Pediatr Crit Care Med. 2002;3:52–6.
6 Fok TF, Monkman S, Dolovich M, Gray S, Coates G, Paes B, et al. Efficiency of aerosol medication delivery from a metered dose inhaler versus jet nebulizer in infants with bronchopulmonary dysplasia. Pediatr Pulmonol. 1996;21:301–9.
7 Erzinger S, Schueepp KG, Brooks-Wildhaber J, Devadason SG, Wildhaber JH. Facemasks and aerosol delivery in vivo. J Aerosol Med. 2007;20:S78–83.
8 Denjean A, Guimaraes H, Migdal M, Miramand JL, Dehan M, Gaultier C. Dose-related bronchodilator response to aerosolized salbutamol (albuterol) in ventilator-dependent premature infants. J Pediatr.1992;120:974–9.